Comments on: Can a male have both the low-risk genital wart causing HPV and the high-risk cervical causing strands of HPV? http://wartstreatments.net/can-a-male-have-both-the-low-risk-genital-wart-causing-hpv-and-the-high-risk-cervical-causing-strands-of-hpv.htm Warts Causes, Symptoms, Treatment & Removal Thu, 09 Feb 2012 02:41:58 -0700 http://wordpress.org/?v=2.8.4 hourly 1 By: tarnishedsilverheart http://wartstreatments.net/can-a-male-have-both-the-low-risk-genital-wart-causing-hpv-and-the-high-risk-cervical-causing-strands-of-hpv.htm/comment-page-1#comment-818 tarnishedsilverheart Fri, 13 Nov 2009 09:48:01 +0000 http://wartstreatments.net/can-a-male-have-both-the-low-risk-genital-wart-causing-hpv-and-the-high-risk-cervical-causing-strands-of-hpv.htm#comment-818 Yes, many men and women with visible genital warts also carry a co-infection with high risk HPV types. Genital warts Condylomata bearing HPV-6 or -11 have identical clinical manifestations and histology [2]. Recent studies have shown that about 100% of GWs are caused by either HPV-6 or -11 but that 20–50% of lesions also contain co-infections with HR HPV types [3] and [4]. GWs do not usually result in major morbidity or mortality, but cause significant psychological morbidity and very substantial healthcare costs. Occasionally GWs persist for long periods of time and, rarely, such long-standing lesions may progress to malignancy. GWs are highly infectious, with a transmission rate of about 65% within sexual partnerships from an infected to a susceptible sexual partner, and an incubation period of between 3 weeks and 8 months, with the majority developing warts at around 2–3 months [3]. Once GWs have developed, they may show minimal change over time, become more numerous or larger, or regress spontaneously. The majority of placebo-controlled GW therapy trials show low rates of regression (around 5% complete clearance) in the short term, although in one study over 16 weeks 20% of women and 5% of men using placebo completely cleared their warts, and 38% of women and 22% of men using placebo cleared over 50% of their baseline warts [3]. Regressing warts contain significantly more CD4 positive T cells, both within the stroma underlying the lesions and the condylomata themselves, and greater expression of activation markers [3]. There is no report of the rate of spontaneous regression that may occur in the longer term. Following GW clearance with therapy, recurrence is common and is often seen within 3 months in 25% of cases, although rates of up to 67% have been observed [3]. In clinical practice recurrences are often seen at sites of previous lesions, and in these cases HPV infection in stem cells or slow-turnover cells at the site of previous clearance has persisted and then reactivated. The proportion of HPV-6/11 infections that are either completely cleared or persist in a latent form after clinical resolution is unknown, and, indeed, animal models suggest that both outcomes can occur [3]. Yes, many men and women with visible genital warts also carry a co-infection with high risk HPV types.

Genital warts
Condylomata bearing HPV-6 or -11 have identical clinical
manifestations and histology [2]. Recent studies have shown that about
100% of GWs are caused by either HPV-6 or -11 but that 20–50% of
lesions also contain co-infections with HR HPV types [3] and [4]. GWs
do not usually result in major morbidity or mortality, but cause
significant psychological morbidity and very substantial healthcare
costs. Occasionally GWs persist for long periods of time and, rarely,
such long-standing lesions may progress to malignancy. GWs are highly
infectious, with a transmission rate of about 65% within sexual
partnerships from an infected to a susceptible sexual partner, and an
incubation period of between 3 weeks and 8 months, with the majority
developing warts at around 2–3 months [3]. Once GWs have developed,
they may show minimal change over time, become more numerous or
larger, or regress spontaneously. The majority of placebo-controlled
GW therapy trials show low rates of regression (around 5% complete
clearance) in the short term, although in one study over 16 weeks 20%
of women and 5% of men using placebo completely cleared their warts,
and 38% of women and 22% of men using placebo cleared over 50% of
their baseline warts [3]. Regressing warts contain significantly more
CD4 positive T cells, both within the stroma underlying the lesions
and the condylomata themselves, and greater expression of activation
markers [3]. There is no report of the rate of spontaneous regression
that may occur in the longer term. Following GW clearance with
therapy, recurrence is common and is often seen within 3 months in 25%
of cases, although rates of up to 67% have been observed [3]. In
clinical practice recurrences are often seen at sites of previous
lesions, and in these cases HPV infection in stem cells or
slow-turnover cells at the site of previous clearance has persisted
and then reactivated. The proportion of HPV-6/11 infections that are
either completely cleared or persist in a latent form after clinical
resolution is unknown, and, indeed, animal models suggest that both
outcomes can occur [3].

]]> By: Eva A http://wartstreatments.net/can-a-male-have-both-the-low-risk-genital-wart-causing-hpv-and-the-high-risk-cervical-causing-strands-of-hpv.htm/comment-page-1#comment-819 Eva A Fri, 13 Nov 2009 09:48:01 +0000 http://wartstreatments.net/can-a-male-have-both-the-low-risk-genital-wart-causing-hpv-and-the-high-risk-cervical-causing-strands-of-hpv.htm#comment-819 Yes, you can carry multiple strains of the virus at the same time. Make sure your partner gets a pap smear at least once a year, so that any cervical changes can be treated before causing cancer. Yes, you can carry multiple strains of the virus at the same time. Make sure your partner gets a pap smear at least once a year, so that any cervical changes can be treated before causing cancer.

]]>